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N,N Carbonyl diimidazole (CDI) (CAS NO : 530-62-1)

N,N Carbonyldiimidazole (CDI) is a high-purity carbonyl activating agent and organic coupling reagent widely used in pharmaceutical, biotechnology, and specialty chemical manufacturing. Chemically classified as a carbonyl diimidazole compound, it functions by activating carboxylic acids to form reactive imidazolide intermediates, enabling efficient amide, ester, carbamate, and urea bond formation under mild conditions without direct biological receptor interaction. Extensively applied in peptide synthesis, API and advanced intermediate production, protein modification, bioconjugation, and nucleic acid derivative synthesis, CDI serves as a synthetic reagent rather than a therapeutic substance. Supplied as a white to off-white crystalline solid, it offers high selectivity, controlled reactivity, and moisture-sensitive physicochemical properties suitable for regulated environments. Each batch undergoes comprehensive quality control including assay, melting range, and impurity profiling, and is supported with Certificate of Analysis (CoA), Safety Data Sheet (SDS), and full traceability documentation. As an established manufacturers and suppliers of N,N Carbonyl diimidazole in the USA, we ensure scalable supply from R&D to commercial volumes with consistent batch performance and reliable lead times with competitive prices (USD).

N,N Carbonyl diimidazole (CDI)
N,N Carbonyl diimidazole (CDI)

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N,N Carbonyldiimidazole (CDI) is a high-purity carbonyl activating agent and organic coupling reagent widely used in pharmaceutical, biotechnology, and specialty chemical manufacturing. Chemically classified as a carbonyl diimidazole compound, it functions by activating carboxylic acids to form reactive imidazolide intermediates, enabling efficient amide, ester, carbamate, and urea bond formation under mild conditions without direct biological receptor interaction. Extensively applied in peptide synthesis, API and advanced intermediate production, protein modification, bioconjugation, and nucleic acid derivative synthesis, CDI serves as a synthetic reagent rather than a therapeutic substance...

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Industry

Pharmaceutical

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Category

Pharmaceutical Actives & Precursors

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Sub-category

Intermediates & Precursors

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Chemical Properties & Specifications

Applications of N,N Carbonyl diimidazole (CDI)

Peptide Synthesis

Primary coupling agent for amino acid activation with minimal racemisation

Pharmaceutical Intermediates

Essential for the synthesis of antibiotics, anti-inflammatory drugs, and complex bioconjugates

Organic Synthesis

Converts amines into ureas and carbamates, and alcohols into esters

Nucleoside Chemistry

Facilitates the activation of phosphates and the synthesis of nucleic acid derivatives

Polymer Science

Cross-linking agents & for surface functionalisation in advanced material science

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