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2-Chloro-5-Iodo benzoic acid (CAS NO : 19904-56-5)

2-Chloro-5-Iodo benzoic acid
2-Chloro-5-Iodo benzoic acid

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Organic Intermediates

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Sub-category

Aromatic Carboxylic Acids & Derivatives

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Chemical Properties & Specifications

Applications of 2-Chloro-5-Iodo benzoic acid

Pharmaceutical API Synthesis

The critical KSM of Empagliflozin and other gliflozin-class medications

Agrochemical Development

Used as a scaffold for next-generation herbicides and fungicides that require specific halogen substitution patterns for bioactivity

Organic Synthesis Research

Preferrence for academic and industrial researchers exploring the kinetics of selective halogen-metal exchange and carboxyl-directed C-H activation

Materials Science

Building block for specialized liquid crystals and organic light-emitting diode (OLED) dopants where high atomic weight atoms (Iodine) are required to tune electronic properties.

Have Questions About 2-Chloro-5-Iodo benzoic acid?
We've Got Answers.

Isomeric impurities (such as the 4-iodo or 6-iodo versions) can lead to inseparable byproducts in the final drug substance.

While the carboxylic acid group must typically be protected (e.g., as an ester), the iodine atom at the 5-position is highly susceptible to magnesium or lithium exchange, allowing for the introduction of various side chains.

Like many iodinated aromatics, it is light-sensitive. We package our 2-Chloro-5-Iodobenzoic Acid in amber glass or light-shielded HDPE containers and recommend storage in a cool, dark environment.

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