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2,4-Diamino-6-Chloropyrimidine 3-Oxide is a pyrimidine derivative primarily used as a reference standard impurity for Minoxidil formulations. It plays a crucial role in impurity profiling and quality control within pharmaceutical manufacturing.
2,4-Diamino-6-Chloropyrimidine 3-Oxide is a pyrimidine derivative primarily used as a reference standard impurity for Minoxidil formulations. It plays a crucial role in impurity profiling and quality control within pharmaceutical manufacturing.
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Beauty & Personal Care
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Hair Care Actives
Hair Regrowth & Scalp Treatment Actives
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Chemical Properties & Specifications
GHS Classification: Not classified as hazardous under GHS.
H302: Harmful if swallowed (applicable under certain test conditions). H315: May cause mild skin irritation.
P264: Wash hands thoroughly after handling. P280: Wear protective gloves and eye protection. P301+P312: If swallowed, call a POISON CENTER or doctor/physician if you feel unwell.
Use PPE when handling the material. Avoid contact with skin and eyes.
Inhalation: Move to fresh air and seek medical attention if symptoms persist. Skin Contact: Wash with soap and water. Remove contaminated clothing. Eye Contact: Rinse cautiously with water for several minutes. Ingestion: Rinse mouth and seek medical advice.
Used in the quality control and impurity profiling of Minoxidil APIs and formulations.
Integrated into the quality assurance process for hair regrowth treatments and scalp health formulations related to Minoxidil-based products.
Store at 2-8°C (refrigerated conditions).
Keep container tightly closed, dry, and away from incompatible materials.
Available in 10 mg, 25 mg, and 100 mg packaging for laboratory and quality control use.
2,4-Diamino-6-Chloropyrimidine 3-Oxide is used as a reference standard impurity in the quality control of Minoxidil API and finished formulations. It helps ensure regulatory compliance by enabling accurate impurity profiling during pharmaceutical manufacturing.
This compound is commonly analyzed using high-performance liquid chromatography (HPLC), providing precise quantification in impurity profiling and stability testing of Minoxidil formulations.
The substance is generally stable under standard laboratory conditions but should be handled with care. Personal protective equipment (PPE) such as gloves, goggles, and lab coats are recommended, and handling should occur in a well-ventilated area to minimize exposure risks.
Monitoring this impurity ensures the safety, efficacy, and quality of Minoxidil-based pharmaceutical products. Controlling impurity levels helps prevent potential adverse effects and ensures compliance with global regulatory standards.
