

Watermelon Ketone (Calone) is being classified for its dual-use in both the Pharmaceutical and Fragrance industries. Calone 1951: The Gold Standard for Aquatic and Marine Synthesis. Calone 1951 is an ultra-pure crystalline intermediate (≥99%) engineered for industries where scent precision and chemical stability are non-negotiable. While legendary in the fragrance industry for creating the "sea breeze" and "watermelon" accords of iconic aquatic perfumes, its unique benzodioxepinone structure also serves as a specialised scaffold in medicinal chemistry research. Whether formulating a high-end luxury fragrance or exploring the bioactivity of oxygen-heterocyclic compounds, our grade provides the olfactory clarity and isomeric purity required for world-class results. We are a globally established Pharmaceutical AND Aroma chemical supplier, along with a broad portfolio of various ‘Intermediates’ worldwide through comprehensive regulatory documentation (CoA), traceability, and consistent global supply capabilities, ensuring reliable lead times and quality assurance across all grades.

Watermelon Ketone (Calone) is being classified for its dual-use in both the Pharmaceutical and Fragrance industries. Calone 1951: The Gold Standard for Aquatic and Marine Synthesis. Calone 1951 is an ultra-pure crystalline intermediate (≥99%) engineered for industries where scent precision and chemical stability are non-negotiable. While legendary in the fragrance industry for creating the "sea breeze" and "watermelon" accords of iconic aquatic perfumes, its unique benzodioxepinone structure also serves as a specialised scaffold in medicinal chemistry research. Whether formulating a high-end luxury fragrance or exploring the bioactivity of oxygen-heterocyclic compounds, our grade provides the olfactory clarity and isomeric purity required for world-class results. We are a globally established Pharmaceutical AND Aroma chemical supplier, along with a broad portfolio of various ‘Intermediates’ worldwide through comprehensive regulatory documentation (CoA), traceability, and consistent global supply capabilities, ensuring reliable lead times and quality assurance across all grades.
Pharmaceutical, Flavors & Fragrances
Fragrance Ingredients, Excipients
Aroma Compounds

Chemical Properties & Specifications
H302 (94.9%): Harmful if swallowed [Warning Acute toxicity, oral]
P264, P270, P301+P317, P330, and P501
Primary "marine" note used to create ozonic, watery, and fresh melon profiles in fine fragrances and soaps
Utilized as a starting material in the study of CNS-active compounds and as a scaffold for investigating oxygen-containing heterocycles
Highly stable in alkaline media, making it ideal for scenting laundry detergents and high-pH cosmetic formulations