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Tembo Acid is a high-speciality fluorinated aromatic carboxylic acid. Within the Agrochemical hierarchy, it is the fundamental "Active Core" used to synthesise the next generation of HPPD-inhibitor herbicides. Design allows for the selective control of broadleaf weeds in corn (Tembotrione) and rice (Fenquinotrione) by disrupting the plant's ability to process sunlight. Source High-Purity Tembo Acid (CAS 120100-77-8) from Scimplify, a premier global manufacturer of HPPD-inhibitor intermediates. As the primary structural backbone for Tembotrione and Fenquinotrione Technical, this advanced benzoic acid derivative is essential for modern high-selectivity weed control. Our bulk Tembo Acid is produced via high-precision fluorination and sulfonation, ensuring the exact placement of the methylsulfonyl and trifluoroethoxy groups. This regio-specific purity is critical for achieving high-yield coupling in the final synthesis of the active ingredient. As a leading speciality agro-intermediate supplier, Scimplify ensures global regulatory compliance, providing the chemical stability, COA/SDS transparency, and reliable bulk lead times required for global crop protection manufacturing
Tembo Acid is a high-speciality fluorinated aromatic carboxylic acid. Within the Agrochemical hierarchy, it is the fundamental "Active Core" used to synthesise the next generation of HPPD-inhibitor herbicides. Design allows for the selective control of broadleaf weeds in corn (Tembotrione) and rice (Fenquinotrione) by disrupting the plant's ability to process sunlight. Source High-Purity Tembo Acid (CAS 120100-77-8) from Scimplify, a premier global manufacturer of HPPD-inhibitor intermediates. As the primary structural backbone for Tembotrione and Fenquinotrione Technical, this advanced benzoic acid derivative is essential for modern high-selectivity weed control. Our bulk Tembo Acid is pro...
Chemical Properties & Specifications
Skin Sens. 1 (100%)
P261, P272, P280, P302+P352, P321, P333+P317, P362+P364, and P501
Benzoic acid-direct precursor-several HPPD-inhibitor herbicides. Works by blocking the enzyme responsible for carotenoid biosynthesis in plants, leading to "bleaching" and eventual death of the weed. Effectiveness against broadleaf weeds in rice and cereal crops
Trifluoroethoxy (CF₃CH₂O-) moiety provides unique lipophilicity and metabolic stability. Intermediate is used in high-end chemical research to study the effects of specific fluorine placement on the bioavailability of aromatic compounds
Contains a carboxylic acid, a chloro group, and a sulfone, this molecule serves as a "scaffold" for multi-step organic synthesis, allowing for selective substitution at different positions on the ring
Very stable under normal conditions. Sulfonyl & trifluoroethoxy groups are robust, though the carboxylic acid group should be protected from highly basic environments during storage
Store in a cool, dry, well-ventilated area (5°C' to 20°C preferred for long-term storage). Keep containers hermetically sealed
Unlike basic benzoic acid, Tembo Acid requires a multi-step synthesis involving selective halogenation, sulfonylation, and a high-precision fluorinated etherification. The cost reflects the complexity of handling trifluoroethanol and the reagents required to place five different functional groups on a single benzene ring without generating unwanted isomers.
Tembo Acid provides the "head" of the molecule that binds to the HPPD enzyme in plants. By blocking this enzyme, the plant cannot produce carotenoids (which protect chlorophyll). Without carotenoids, the sunlight destroys the chlorophyll, turning the weed white—a process known as bleaching.
We maintain a moisture limit of ≤ 0.5%. Higher moisture content can interfere with the formation of the final herbicide active, especially during the dehydration or coupling steps in the reactor.
Yes. Under current GHS and IMDG guidelines, Tembo Acid is generally classified as non-hazardous for transport, though it is treated as a specialty chemical with strict storage requirements to maintain its crystalline purity.
Yes. CAS 120100-77-8 serves as the critical acid intermediate for both. The difference in the final herbicide depends on the "pairing" molecule: Tembotrione is formed by coupling this acid with 1,3-cyclohexanedione, whereas Fenquinotrione involves a different heterocyclic coupling.
Yes. The ether linkage in Tembo Acid is engineered for high stability. However, to maintain the integrity of the fluorinated side chain, the coupling reaction should be performed under anhydrous conditions with precise temperature control to avoid any side-chain hydrolysis.
The 2-chloro position is vital. It creates the necessary steric hindrance that allows the molecule to fit perfectly into the HPPD enzyme's active site. Scimplify's process guarantees that the chlorine atom is exclusively in the 2-position, ensuring the maximum biological "knock-down" effect of the final herbicide.
Due to the complexity of the multi-step synthesis (particularly the fluorination step), we typically maintain a 8–10 week lead time for large bulk orders. We recommend establishing a rolling forecast to ensure a consistent supply for your technical-grade production campaigns.
Tembotrione Intermediate Price 2026 for High Purity Tembotrione Acid >98% Bulk and MOQ shared upon on sourcing with procurement managers with Tembo Acid, coa, sds along with regulatory compliances.
