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2-Chloro-3-Nitropyridine is a highly versatile heterocyclic building block characterised by its dual-functionalised ring system. Pyridine, 2chloro3nitroc's presence of both a highly reactive chlorine atom at the C2 position and a strong electron-withdrawing nitro group at C3 creates a "hotspot" for regioselective chemical diversity. We utilise world-class manufacturing infrastructure to deliver this intermediate with ultra-low moisture content and a controlled impurity profile, ensuring seamless integration into your GMP or ISO-certified production lines. Preferred starting material for complex molecules requiring ortho-substitution patterns on a pyridine core. We are an established 2-Chloro-3-Nitropyridine manufacturer at 99%+ purity, ensuring minimal carry-over of impurities in the final API, and a broad range of various agrochemical intermediates providing comprehensive analytical (HPLC/NMR/MS) and supporting quality assurance documentation (COA/TDS/SDS) across all grades, detailed impurity mapping, and region-specific regulatory support. We ensure reliable lead times from R&D quantities through commercial-scale manufacturing, enabling partners to meet diverse global and regional requirements.
2-Chloro-3-Nitropyridine is a highly versatile heterocyclic building block characterised by its dual-functionalised ring system. Pyridine, 2chloro3nitroc's presence of both a highly reactive chlorine atom at the C2 position and a strong electron-withdrawing nitro group at C3 creates a "hotspot" for regioselective chemical diversity. We utilise world-class manufacturing infrastructure to deliver this intermediate with ultra-low moisture content and a controlled impurity profile, ensuring seamless integration into your GMP or ISO-certified production lines. Preferred starting material for complex molecules requiring ortho-substitution patterns on a pyridine core. We are an established 2-Chloro...
Chemical Properties & Specifications
Acute Tox. 3 (83.7%), Acute Tox. 4 (12.2%), Skin Irrit. 2 (100%), Eye Irrit. 2 (100%), STOT SE 3 (98%)
P261, P264, P264+P265, P270, P271, P280, P301+P316, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501
Pivotal intermediate in the production of JAK inhibitors (e.g., Tofacitinib), anti-retroviral drugs (e.g., Nevirapine), and various kinase inhibitors
2,4,6-Collidine (Symmetrical Trimethylpyridine) - Gold Standard - sterically hindered base used in organic synthesis, particularly in the protection of alcohols (TBS/TMS ethers) and peptide coupling
Development of next-generation herbicides and fungicides that require specific nitrogen-heterocyclic cores
Precursors for specialised ligands in coordination chemistry and high-performance organic electronics (OLEDs)
Quantity: We are currently fulfilling requirements for up to 5 MT.
Timeline: Standard lead time is 7-8 Weeks for high-purity industrial batches.
Packaging & Logistics: Supplied in HDPE Drums on an Ex-Works Hyderabad basis.
Ortho-relationship between the Chlorine and Nitro groups is critical. In industrial medicinal chemistry, a Nucleophilic Aromatic Substitution is typically performed on the chlorine atom, followed by a reduction of the nitro group. This sequence allows for the rapid construction of fused rings like pyrazolopyridines, which are essential motifs in modern oncology and immunology drugs.
Absolutely. Every batch shipped in our HDPE Drums is accompanied by a comprehensive CoA. We pay particular attention to moisture levels (typically <0.5%) and specific isomeric impurities. For scientists, this means the Nucleophilic Aromatic Substitution (SNAr) kinetics remain predictable. For procurement, it ensures compliance with the strict "Material Intake" specifications required by GMP facilities.
Yes. Being located in a global pharmaceutical hub like Hyderabad, our Ex-Works model allows for seamless transition to Air or Sea freight via international ports. We provide all necessary export documentation, including GHS-compliant labeling and MSDS, to ensure hassle-free customs clearance for buyers in the EU, SE Asia, and ROW segments.
Many suppliers can provide gram-scale samples, but few can maintain the same Impurity Profile at a 5MT scale. We solve this "Scale-Up Gap" by utilising a validated, robust manufacturing process. We offer Batch-to-Batch Consistency data, allowing your Process Engineers to lock in their parameters without worrying about new, unexpected impurities appearing as you move from Pilot to Commercial phase.
As a yellowish crystalline solid that can sublime, it requires storage in cool, dry, and well-ventilated areas.Our HDPE Drum packaging is specifically selected for its chemical resistance and moisture-barrier properties. We provide detailed handling instructions to ensure your warehouse personnel remain safe and the product integrity is preserved for the full 7-8 week transit and storage period
